The Angiopoietin-2 Polyclonal Antibody (CAB0698) is a valuable tool for researchers studying angiopoietin-2, a key player in angiogenesis and vascular development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.Angiopoietin-2 is a critical regulator of blood vessel formation and remodeling, making it an important target for investigating diseases such as cancer, cardiovascular disorders, and inflammatory conditions. By targeting angiopoietin-2, researchers can gain insights into the mechanisms underlying these diseases and potentially develop novel therapeutic strategies.
This polyclonal antibody specifically recognizes angiopoietin-2, allowing for precise detection and analysis in different cell types and tissues. Its reliability and specificity make it an indispensable tool for studies in vascular biology, oncology, and other fields related to angiogenesis. By utilizing the Angiopoietin-2 Polyclonal Antibody (CAB0698), researchers can advance their understanding of angiopoietin-2's role in health and disease, paving the way for innovative treatment approaches.
Product Name:
ANGPT2 Rabbit Polyclonal Antibody
SKU:
CAB0698
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 197-496 of human ANGPT2 (NP_001138.1).
This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
Purification Method:
Affinity purification
Gene ID:
285
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANGPT2 Rabbit pAb (CAB0698) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
