ANGPT1 Rabbit Monoclonal Antibody (CAB3757)
- SKU:
- CAB3757
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
Product Name: | ANGPT1 Rabbit Monoclonal Antibody |
SKU: | CAB3757 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ANGPT1 (Q15389). |
Sequence: | EMEG KHKE ELDT LKEE KENL QGLV TRQT YIIQ ELEK QLNR ATTN NSVL QKQQ LELM DTVH NLVN LCTK EGVL LKGG KREE EKPF RDCA DVYQ AGFN KSGI Y |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | AGP1; AGPT; ANG1; HAE5; AGPT-1; ANGPT1 |
Positive Sample: | Mouse lung,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 58kDa |
Observed MW: | 70kDa |
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.
Purification Method: | Affinity purification |
Gene ID: | 284 |
Clone Number: | ARC0248 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |