The Angpt1 Rabbit Monoclonal Antibody (CAB3757) is a cutting-edge tool for researchers studying Angiopoietin-1 (Angpt1), a protein known for its role in angiogenesis and vascular development. This antibody, produced using rabbit monoclonal technology, exhibits high specificity and sensitivity towards Angpt1 in human samples, making it an excellent choice for various applications such as immunohistochemistry and flow cytometry.Angpt1 is a critical regulator of blood vessel formation and maintenance, making it a key player in processes like wound healing, organ development, and tumor growth. By targeting Angpt1 with this antibody, researchers can investigate its functions in different cell types and disease contexts, thereby advancing our understanding of angiogenesis-related disorders and potential therapeutic interventions.
With its superior performance and reliability, the Angpt1 Rabbit Monoclonal Antibody (CAB3757) is a valuable tool for scientists conducting research in the fields of vascular biology, cancer biology, and regenerative medicine. Its ability to specifically detect Angpt1 protein expression opens up new possibilities for unraveling the complex mechanisms underlying vascular development and disease progression.
Product Name:
ANGPT1 Rabbit Monoclonal Antibody
SKU:
CAB3757
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ANGPT1 (Q15389).
Sequence:
EMEG KHKE ELDT LKEE KENL QGLV TRQT YIIQ ELEK QLNR ATTN NSVL QKQQ LELM DTVH NLVN LCTK EGVL LKGG KREE EKPF RDCA DVYQ AGFN KSGI Y
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:
AGP1; AGPT; ANG1; HAE5; AGPT-1; ANGPT1
Positive Sample:
Mouse lung,Rat kidney
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
58kDa
Observed MW:
70kDa
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.
Purification Method:
Affinity purification
Gene ID:
284
Clone Number:
ARC0248
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANGPT1 Rabbit mAb (CAB3757) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
