ANGPT1 Rabbit Polyclonal Antibody (CAB7877)
- SKU:
- CAB7877
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Description
Product Name: | ANGPT1 Rabbit Polyclonal Antibody |
SKU: | CAB7877 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-498 of human ANGPT1 (NP_001137.2). |
Sequence: | REEE KPFR DCAD VYQA GFNK SGIY TIYI NNMP EPKK VFCN MDVN GGGW TVIQ HRED GSLD FQRG WKEY KMGF GNPS GEYW LGNE FIFA ITSQ RQYM LRIE LMDW EGNR AYSQ YDRF HIGN EKQN YRLY LKGH TGTA GKQS SLIL HGAD FSTK DADN DNCM CKCA LMLT GGWW FDAC GPSN LNGM FYTA GQNH GKLN GIKW HYFK GPSY SLRS TTMM IRPL DF |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:100 |
Synonyms: | AGP1; AGPT; ANG1; HAE5; AGPT-1; ANGPT1 |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 58kDa |
Observed MW: | 70kDa |
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.
Purification Method: | Affinity purification |
Gene ID: | 284 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |