[KO Validated] AMOT Rabbit Polyclonal Antibody (CAB8075)
- SKU:
- CAB8075
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] AMOT Rabbit Polyclonal Antibody |
SKU: | CAB8075 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AMOT (NP_573572.1). |
Sequence: | MPRA QPSS ASYQ PVPA DPFA IVSR AQQM VEIL SDEN RNLR QELE GCYE KVAR LQKV ETEI QRVS EAYE NLVK SSSK REAL EKAM RNKL EGEI RRMH DFNR DLRE RLET ANKQ LAEK EYEG SEDT RKTI SQLF AKNK ESQR EKEK LEAE LATA RSTN EDQR RHIE IRDQ ALSN AQAK VVKL EEEL KKKQ VYVD KVEK MQQA LVQL QAAC EKRE QLEH RLRT RLER ELES LRIQ QRQG NCQP TNVS EYNA AALM ELLR EKEE RILA LEAD MTKW EQKY LEEN VMRH FALD AAAT VAAQ RDTT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AMOT |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, tight junction. |
Calculated MW: | 118kDa |
Observed MW: | 130-140kDa |
This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 154796 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |