ANAPC2 Rabbit Polyclonal Antibody (CAB8066)
- SKU:
- CAB8066
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | ANAPC2 Rabbit Polyclonal Antibody |
SKU: | CAB8066 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ANAPC2 (NP_037498.1). |
Sequence: | YISA IKAL RVLD PSMV ILEV ACEP IRRY LRTR EDTV RQIV AGLT GDSD GTGD LAVE LSKT DPAS LETG QDSE DDSG EPED WVPD PVDA DPGK SSSK RRSS D |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 |
Synonyms: | APC2; ANAPC2 |
Positive Sample: | Mouse brian,Mouse kidney,Rat brian,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nucleoplasm |
Calculated MW: | 94kDa |
Observed MW: | 102kDa |
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
Purification Method: | Affinity purification |
Gene ID: | 29882 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |