The ANAPC11 Polyclonal Antibody (CAB15449) is a valuable tool for researchers studying ANAPC11, a key protein involved in cell cycle regulation and cell division. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot experiments. By targeting the ANAPC11 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and cancer research.ANAPC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a crucial regulator of the cell cycle that controls the progression of cells through mitosis and ensures accurate chromosome segregation.
Dysregulation of ANAPC11 has been linked to abnormalities in cell division, leading to potential implications in cancer development and other diseases. Research into ANAPC11 function is essential for understanding the mechanisms governing cell growth and division, with potential implications for therapeutic interventions targeting cell cycle abnormalities.
Product Name:
ANAPC11 Rabbit Polyclonal Antibody
SKU:
CAB15449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-84 of human ANAPC11 (NP_001002245.1).
Enables cullin family protein binding activity and ubiquitin-ubiquitin ligase activity. Contributes to ubiquitin-protein transferase activity. Involved in protein K11-linked ubiquitination. Located in nucleolus and nucleoplasm. Part of anaphase-promoting complex.
Purification Method:
Affinity purification
Gene ID:
51529
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using ANAPC11 Rabbit pAb (CAB15449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 120s.
