The AMY1A Polyclonal Antibody (CAB13276) is specifically designed for research involving AMY1A, a gene encoding the salivary alpha-amylase enzyme that plays a crucial role in the digestion of dietary starch. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in various applications, including immunohistochemistry and ELISA.AMY1A is a key enzyme in the breakdown of complex carbohydrates in the saliva, initiating the process of starch digestion in the mouth. Its activity is essential for proper nutrient absorption and overall digestive health.
Research on AMY1A can provide insights into the mechanisms of carbohydrate metabolism and the impact of genetic variations on individual dietary requirements.Furthermore, dysregulation of AMY1A expression has been implicated in various metabolic disorders, such as obesity, type 2 diabetes, and pancreatic diseases. Understanding the role of AMY1A in these conditions may lead to the development of targeted therapies or personalized dietary interventions. The AMY1A Polyclonal Antibody is a valuable tool for investigating the functions and implications of AMY1A in health and disease.
Product Name:
AMY1A Rabbit Polyclonal Antibody
SKU:
CAB13276
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 16-200 of human AMY1A (NP_004029.2).
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
276
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using AMY1A antibody (CAB13276) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
