UniProt Protein Function: | AMTN: Could be a cell adhesion protein involved in the maturation of tooth enamel. Belongs to the amelotin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Extracellular matrix; Secreted; Secreted, signal peptide; Cell adhesionChromosomal Location of Human Ortholog: 4q13.3Cellular Component: basal lamina; intercellular junction; proteinaceous extracellular matrixBiological Process: odontogenesis of dentine-containing teeth |
UniProt Protein Details: | |
NCBI Summary: | The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6UX39 |
NCBI GenInfo Identifier: | 55976710 |
NCBI Gene ID: | 401138 |
NCBI Accession: | Q6UX39.1 |
UniProt Secondary Accession: | Q6UX39,Q0P503, Q0P506 |
UniProt Related Accession: | Q6UX39 |
Molecular Weight: | 21,459 Da |
NCBI Full Name: | Amelotin |
NCBI Synonym Full Names: | amelotin |
NCBI Official Symbol: | AMTNÂ Â |
NCBI Official Synonym Symbols: | UNQ689Â Â |
NCBI Protein Information: | amelotin |
UniProt Protein Name: | Amelotin |
UniProt Synonym Protein Names: | |
Protein Family: | Amelotin |
UniProt Gene Name: | AMTNÂ Â |
UniProt Entry Name: | AMTN_HUMAN |