AMPKa1/AMPKa2 Polyclonal Antibody (CAB17289)
- SKU:
- CAB17289
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | AMPKa1/AMPKa2 Polyclonal Antibody |
SKU: | CAB17289 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 5-280 of human AMPKa1/AMPKa2 (NP_006242.5). |
Sequence: | SSWR KMAT AEKQ KHDG RVKI GHYI LGDT LGVG TFGK VKVG KHEL TGHK VAVK ILNR QKIR SLDV VGKI RREI QNLK LFRH PHII KLYQ VIST PSDI FMVM EYVS GGEL FDYI CKNG RLDE KESR RLFQ QILS GVDY CHRH MVVH RDLK PENV LLDA HMNA KIAD FGLS NMMS DGEF LRTS CGSP NYAA PEVI SGRL YAGP EVDI WSSG VILY ALLC GTLP FDDD HVPT LFKK ICDG IFYT PQYL NPSV ISLL KHML QVDP MKRA TIKD IREH EWFK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AMPKa1/AMPKa2 |
Positive Sample: | MCF7,Mouse liver,Mouse brain,C2C12,Rat liver |
Cellular Localization: | apical plasma membrane, cytoplasm, cytosol, nuclear speck, nucleoplasm, nucleus |
Calculated MW: | 64kDa/65kDa |
Observed MW: | 62kDa |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5562/5563 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |