AMPKα1 Polyclonal Antibody (CAB21813)
- SKU:
- CAB21813
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | AMPKα1 Polyclonal Antibody |
SKU: | CAB21813 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | IgG |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human AMPKα1 (NP_006242.5). |
Sequence: | IFMV MEYV SGGE LFDY ICKN GRLD EKES RRLF QQIL SGVD YCHR HMVV HRDL KPEN VLLD AHMN AKIA DFGL SNMM SDGE FLRT SCGS PNYA APEV ISGR L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | AMPK; AMPKa1; AMPK alpha 1; AMPKα1 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, cytoplasm, cytosol, nuclear speck, nucleoplasm, nucleus |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5562 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |