AMPKγ1 Polyclonal Antibody (CAB22024)
- SKU:
- CAB22024
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | AMPKγ1 Polyclonal Antibody |
SKU: | CAB22024 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human AMPKγ1 (NP_002724.1). |
Sequence: | KSAL VQIY ELEE HKIE TWRE VYLQ DSFK PLVC ISPN ASLF DAVS SLIR NKIH RLPV IDPE SGNT LYIL THKR ILKF LKLF ITEF PKPE FMSK SLEE LQIG T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | AMPKG; AMPKγ1 |
Positive Sample: | Jurkat,K562,HeLa,Mouse kidney,Mouse lung,Rat kidney,Rat lung,Jurkat,K-562,HeLa,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleoplasm, nucleus |
Calculated MW: | 38kDa |
Observed MW: | 37kDa/ |
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5571 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |