The Amphiregulin Polyclonal Antibody (CAB1860) is a valuable tool for researchers studying the role of amphiregulin in various cellular processes. Amphiregulin is a member of the epidermal growth factor family and is known for its role in cell proliferation, differentiation, and migration.This polyclonal antibody, raised in rabbits, is highly specific and reactive with human samples. It is suitable for use in Western blot applications, allowing for the detection and analysis of amphiregulin protein in different cell types.
This makes it an ideal choice for studies in the fields of cancer research, developmental biology, and tissue regeneration.Amphiregulin is implicated in various physiological and pathological processes, including wound healing, inflammation, and cancer progression. By using this antibody, researchers can gain valuable insights into the mechanisms by which amphiregulin functions in these contexts. This knowledge is critical for the development of targeted therapies for diseases where amphiregulin plays a significant role.
Product Name:
Amphiregulin Rabbit Polyclonal Antibody
SKU:
CAB1860
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human Amphiregulin (NP_001648.1).
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Purification Method:
Affinity purification
Gene ID:
374
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using Amphiregulin Rabbit pAb (CAB1860) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
