Amphiregulin Rabbit Polyclonal Antibody (CAB1860)
- SKU:
- CAB1860
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Amphiregulin Rabbit Polyclonal Antibody |
SKU: | CAB1860 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human Amphiregulin (NP_001648.1). |
Sequence: | SGHY AAGL DLND TYSG KREP FSGD HSAD GFEV TSRS EMSS GSEI SPVS EMPS SSEP SSGA DYDY SEEY DNEP QIPG YIVD DSVR VEQV VKPP QNKT ESEN TSDK PKRK KKGG KNGK NRRN RKKK NPCN AEFQ NFCI HGEC KYIE HLEA VTCK CQQE YFGE RCGE KSMK THSM IDSS LSKI ALAA IAAF MSAV ILTA VAVI TVQL RRQY VRKY EGEA EERK KLRQ ENGN VHAI A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AR; SDGF; AREGB; CRDGF; Amphiregulin |
Positive Sample: | A-549,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass membrane protein. |
Calculated MW: | 28kDa |
Observed MW: | 43kDa |
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Purification Method: | Affinity purification |
Gene ID: | 374 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |