AMPD1 Rabbit Polyclonal Antibody (CAB3584)
- SKU:
- CAB3584
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | AMPD1 Rabbit Polyclonal Antibody |
SKU: | CAB3584 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human AMPD1 (NP_001166097.1). |
Sequence: | AEKV FASE VKDE GGRQ EISP FDVD EICP ISHH EMQA HIFH LETL STST EARR KKRF QGRK TVNL SIPL SETS STKL SHID EYIS SSPT YQTV PDFQ RVQI TGDY ASGV TVED FEIV CKGL YRAL CIRE KYMQ KSFQ RFPK TPSK YLRN IDGE AWVA NESF YPVF TPPV KKGE DPFR TDNL PENL GYHL KMKD GVVY VYPN EAAV SKDE PKP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MAD; MADA; MMDD; AMPD1 |
Positive Sample: | A375,SKOV3,A-549,Mouse heart,Mouse lung,Rat skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 86kDa |
Observed MW: | 80kDa |
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Purification Method: | Affinity purification |
Gene ID: | 270 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |