The AMPD1 Polyclonal Antibody (CAB3584) is a valuable tool for researchers studying AMPD1, an enzyme involved in purine metabolism and cellular energy regulation. This antibody, produced using rabbit immunization, exhibits high reactivity with human samples and is validated for use in Western blot applications, allowing for the specific detection of AMPD1 protein levels.AMPD1 is essential for maintaining cellular energy balance and has been implicated in various diseases, including metabolic disorders and cardiac conditions. By targeting AMPD1, researchers can gain insights into its role in cellular metabolism and potential implications for disease development.
This antibody enables the accurate detection and analysis of AMPD1 in a range of cell types, making it ideal for studies in metabolism, cardiovascular health, and related research areas.Understanding the function and regulation of AMPD1 is crucial for advancing our knowledge of cellular energy metabolism and its impact on human health. By utilizing the AMPD1 Polyclonal Antibody, researchers can further investigate the intricate mechanisms underlying purine metabolism and its implications for disease states, offering new insights and potential therapeutic targets for future studies.
Product Name:
AMPD1 Rabbit Polyclonal Antibody
SKU:
CAB3584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human AMPD1 (NP_001166097.1).
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Purification Method:
Affinity purification
Gene ID:
270
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AMPD1 antibody (CAB3584) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
