The AMP Deaminase 3 Polyclonal Antibody (CAB6354) is a valuable tool for researchers investigating AMP Deaminase 3, an enzyme involved in nucleotide metabolism. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically targeting AMP Deaminase 3, researchers can efficiently detect and analyze this protein in a variety of cell types, making it an excellent choice for studies in biochemistry and molecular biology.
AMP Deaminase 3 is a key player in nucleotide metabolism, playing a crucial role in maintaining cellular energy balance. Dysfunction or dysregulation of this enzyme has been linked to various diseases, including metabolic disorders and muscle-related conditions. By studying the function and regulation of AMP Deaminase 3, researchers can gain valuable insights into these pathological processes and potentially develop targeted therapies to treat associated disorders.
Product Name:
AMPD3 Rabbit Polyclonal Antibody
SKU:
CAB6354
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1).
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Purification Method:
Affinity purification
Gene ID:
272
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using AMPD3 Rabbit pAb (CAB6354) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
