The AMOTL1 Polyclonal Antibody (CAB18112) is a valuable tool for researchers studying the AMOTL1 protein, a key player in cellular processes such as cell proliferation, migration, and adhesion. The antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the AMOTL1 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential component in studies related to cell biology and cancer research.
AMOTL1, also known as Angiomotin-like protein 1, is involved in multiple signaling pathways that regulate cell growth, tissue development, and tumor progression. Its role in promoting or inhibiting these processes makes it a potential target for therapeutic interventions in conditions like cancer and cardiovascular diseases. Understanding the function of AMOTL1 is crucial for developing effective treatments that can modulate its activity and potentially improve patient outcomes.
Product Name:
AMOTL1 Rabbit Polyclonal Antibody
SKU:
CAB18112
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 810-900 of human AMOTL1 (NP_570899.1).
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
154810
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AMOTL1 Rabbit pAb (CAB18112) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
