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AMOT Polyclonal Antibody (CAB21843)

SKU:
CAB21843
$155
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Description

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Product Name:AMOT Polyclonal Antibody
SKU:CAB21843
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1000-1084 of human AMOT (NP_001106962.1).
Sequence:QTQA PTSA PAVA PTPA PTPT PAVA QAEV PASP ATGP GPHR LSIP SLTC NPDK TDGP VFHS NTLE RKTP IQIL GQEP DAEM VEYL I
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:AMOT; angiomotin
Positive Sample:Mouse lung
Conjugate:Unconjugated
Cellular Localization:Cell junction, tight junction.
Calculated MW:118kDa
Observed MW:130kDa

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:154796
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse lung using AMOT Rabbit pAb(CAB21843) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 120s.

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