Description
Product Name: | AMOT Polyclonal Antibody |
SKU: | CAB21843 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1000-1084 of human AMOT (NP_001106962.1). |
Sequence: | QTQA PTSA PAVA PTPA PTPT PAVA QAEV PASP ATGP GPHR LSIP SLTC NPDK TDGP VFHS NTLE RKTP IQIL GQEP DAEM VEYL I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AMOT; angiomotin |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, tight junction. |
Calculated MW: | 118kDa |
Observed MW: | 130kDa |
This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 154796 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |