Amh Antibody (PACO24892)
- SKU:
- PACO24892
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Amh Antibody (PACO24892)
The AMH Polyclonal Antibody (PACO24892) is a valuable tool for researchers studying Anti-Mullerian Hormone (AMH), a protein involved in reproductive health and development. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in applications such as Western blotting.AMH is a key regulator of sexual differentiation and fertility, making it a vital molecule to study in the fields of reproductive biology and endocrinology. Its levels have been linked to conditions such as polycystic ovary syndrome (PCOS) and ovarian reserve, highlighting its importance in understanding female reproductive health.
By using the AMH Polyclonal Antibody, researchers can detect and analyze AMH protein in various cell types, providing valuable insights into its role in reproductive function and potential implications for fertility treatments and hormonal disorders. This antibody is a valuable tool for investigating the complex mechanisms of AMH in health and disease.
| Antibody Name: | Amh Antibody (PACO24892) |
| Antibody SKU: | PACO24892 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:10-1:100 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse Muellerian-inhibiting factor protein (450-552AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO24892 at dilution of 1:10. |
 | Western Blot Positive WB detected in: Mouse kidney tissue All lanes: Amh antibody at 2.7µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 60 kDa Observed band size: 60 kDa . |
| Background: | This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. |
| Synonyms: | Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS), Amh |
| UniProt Protein Function: | AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Cellular Component: cytoplasm; extracellular space Molecular Function:hormone activity; receptor binding; transforming growth factor beta receptor binding Biological Process: activation of NF-kappaB transcription factor; cell-cell signaling; Mullerian duct regression; preantral ovarian follicle growth; urogenital system development |
| NCBI Summary: | This gene is a member of the transforming growth factor-beta superfamily of growth and differentiation factors. The encoded protein is produced in fetal Sertoli cells during male gonadal differentiation. The protein binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in developing male embryos. In humans, some mutations in this gene are associated with persistent Mullerian duct syndrome (PMDS). [provided by RefSeq, Apr 2013] |
| UniProt Code: | P27106 |
| NCBI GenInfo Identifier: | 127110 |
| NCBI Gene ID: | 11705 |
| NCBI Accession: | P27106.1 |
| UniProt Related Accession: | P27106 |
| Molecular Weight: | 11.3 kDa |
| NCBI Full Name: | Muellerian-inhibiting factor |
| NCBI Synonym Full Names: | anti-Mullerian hormone |
| NCBI Official Symbol: | Amh  |
| NCBI Official Synonym Symbols: | MISÂ Â |
| NCBI Protein Information: | muellerian-inhibiting factor |
| UniProt Protein Name: | Muellerian-inhibiting factor |
| UniProt Synonym Protein Names: | Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS |
| Protein Family: | Muellerian-inhibiting factor |
| UniProt Gene Name: | Amh  |
| UniProt Entry Name: | MIS_MOUSE |
| ELISA Kits |
| Mouse AMH (Anti-Mullerian Hormone) CLIA Kit (MOES00079) |
| Mouse Muellerian-inhibiting factor (Amh) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human MIS / AMH ELISA Kit
Human Anti-Mullerian Hormone (AMH) ELISA Kit
Human AMH (Anti-Mullerian Hormone) ELISA Kit
Rat Anti Mullerian Hormone (AMH) ELISA Kit
