The AMFR Polyclonal Antibody (CAB3731) is a valuable tool for researchers studying the AMFR protein, which plays a key role in protein ubiquitination and regulation of cellular processes. This polyclonal antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blotting applications. By binding to the AMFR protein, this antibody enables researchers to detect and study AMFR expression in various cell types, making it an ideal choice for studies in cell biology and cancer research.AMFR, also known as the autocrine motility factor receptor, is involved in the regulation of cell migration, adhesion, and invasion, making it an important target for understanding cancer progression and metastasis.
Research on AMFR is vital for developing new therapies that target this protein and its signaling pathways, with potential applications in cancer treatment and metastasis prevention. The AMFR Polyclonal Antibody (CAB3731) provides researchers with a reliable tool for investigating the role of AMFR in cellular processes and disease pathogenesis.
Product Name:
AMFR Rabbit Polyclonal Antibody
SKU:
CAB3731
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 384-643 of human AMFR (NP_001135.3).
This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
Purification Method:
Affinity purification
Gene ID:
267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AMFR antibody (CAB3731) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
