AMDHD2 Antibody (PACO15419)
- SKU:
- PACO15419
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | AMDHD2 Antibody (PACO15419) |
| Antibody SKU: | PACO15419 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human AMDHD2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15419(AMDHD2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: mouse heart tissue, Mouse liver tissue, Primary antibody: PACO15419(AMDHD2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15419(AMDHD2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid, (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. |
| Synonyms: | amidohydrolase domain containing 2 |
| UniProt Protein Function: | AMDHD2: Belongs to the NagA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 3.5.1.25Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: cytosol; nucleusMolecular Function: N-acetylglucosamine-6-phosphate deacetylase activity; protein bindingBiological Process: N-acetylglucosamine catabolic process; N-acetylneuraminate catabolic process; UDP-N-acetylglucosamine biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y303 |
| NCBI GenInfo Identifier: | 166233266 |
| NCBI Gene ID: | 51005 |
| NCBI Accession: | Q9Y303.2 |
| UniProt Secondary Accession: | Q9Y303,Q8WV54, B4DL77 |
| UniProt Related Accession: | Q9Y303 |
| Molecular Weight: | 63,595 Da |
| NCBI Full Name: | N-acetylglucosamine-6-phosphate deacetylase |
| NCBI Synonym Full Names: | amidohydrolase domain containing 2 |
| NCBI Official Symbol: | AMDHD2Â Â |
| NCBI Official Synonym Symbols: | CGI-14Â Â |
| NCBI Protein Information: | N-acetylglucosamine-6-phosphate deacetylase |
| UniProt Protein Name: | N-acetylglucosamine-6-phosphate deacetylase |
| UniProt Synonym Protein Names: | Amidohydrolase domain-containing protein 2Curated |
| Protein Family: | |
| UniProt Gene Name: | AMDHD2Â Â |
| UniProt Entry Name: | NAGA_HUMAN |
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