Anti-AMDHD2 Antibody (PACO15419)

AMDHD2 Antibody (PACO15419)

SKU:

PACO15419

Product Type:

Antibody

Reactivity:

Human

Mouse

Rat

Host Species:

Rabbit

Isotype:

IgG

Applications:

ELISA

IHC

Antibody Type:

Polyclonal Antibody

Conjugation:

Unconjugated

Description

Description

DatasheetMSDS

AMDHD2 Antibody (PACO15419)

The AMDHD2 Polyclonal Antibody (PAC015419) is a valuable tool for researchers studying AMDHD2, a key enzyme involved in amino acid metabolism. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding to the AMDHD2 protein, this antibody facilitates detection and analysis in various cell types, making it a versatile option for studies in metabolic disorders, cancer research, and other related fields.

AMDHD2 is essential for the breakdown of amino acids and plays a crucial role in maintaining metabolic balance within cells. Dysregulation of AMDHD2 has been linked to disorders such as hyperammonemia and urea cycle disorders, making it a promising target for therapeutic interventions. Understanding the function and regulation of AMDHD2 is vital for developing strategies to treat these conditions and improve metabolic health.

AMDHD2 Antibody (PACO15418)

€339

Product Code:

PACO15418

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

Human AMDHD2 (N-acetylglucosamine-6-phosphate deacetylase) ELISA KIT (HUFI08245)

€599

Product Code:

HUFI08245

ELISA Type:

Sandwich

Sensitivity:

0.094ng/ml

Range:

0.156-10ng/ml

IHC image of PACO64881 diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG labeled by HRP and visualized using 0.05% DAB. — Choose Options

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OSTN Antibody (PACO64881)

€339

Product Code:

PACO64881

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of PC3 cells with PACO64877 at 1:100, counter-stained with DAPI. The cells were blocked in 10% normal Goat Serum and incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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OR9G1 Antibody (PACO64877)

€339

Product Code:

PACO64877

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: Escherichia coli lysate<br />
All lanes: ompF antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 40 kDa<br />
Observed band size: 40 kDa<br /> — Choose Options

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ompF Antibody (PACO64865)

€339

Product Code:

PACO64865

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of A549 cells with PACO64597 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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ANKEF1 Antibody (PACO64597)

€339

Product Code:

PACO64597

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: A549 whole cell lysate, Mouse liver tissue<br />
All lanes: CYP2A13 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 57 kDa<br />
Observed band size: 57 kDa<br /> — Choose Options

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CYP2A13 Antibody (PACO64657)

€319

Product Code:

PACO64657

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of MCF-7 cells with PACO64925 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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RIMS4 Antibody (PACO64925)

€319

Product Code:

PACO64925

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: Mouse heart tissue,Mouse kidney tissue<br />
All lanes: ompF antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 57 kDa<br />
Observed band size: 57 kDa<br /> — Choose Options

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Ang4 Antibody (PACO64593)

€339

Product Code:

PACO64593

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Antibody Name:	AMDHD2 Antibody (PACO15419)
Antibody SKU:	PACO15419
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Fusion protein of human AMDHD2

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid, (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.
Synonyms:	amidohydrolase domain containing 2

UniProt Protein Function:	AMDHD2: Belongs to the NagA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 3.5.1.25Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: cytosol; nucleusMolecular Function: N-acetylglucosamine-6-phosphate deacetylase activity; protein bindingBiological Process: N-acetylglucosamine catabolic process; N-acetylneuraminate catabolic process; UDP-N-acetylglucosamine biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q9Y303
NCBI GenInfo Identifier:	166233266
NCBI Gene ID:	51005
NCBI Accession:	Q9Y303.2
UniProt Secondary Accession:	Q9Y303,Q8WV54, B4DL77
UniProt Related Accession:	Q9Y303
Molecular Weight:	63,595 Da
NCBI Full Name:	N-acetylglucosamine-6-phosphate deacetylase
NCBI Synonym Full Names:	amidohydrolase domain containing 2
NCBI Official Symbol:	AMDHD2
NCBI Official Synonym Symbols:	CGI-14
NCBI Protein Information:	N-acetylglucosamine-6-phosphate deacetylase
UniProt Protein Name:	N-acetylglucosamine-6-phosphate deacetylase
UniProt Synonym Protein Names:	Amidohydrolase domain-containing protein 2Curated
Protein Family:
UniProt Gene Name:	AMDHD2
UniProt Entry Name:	NAGA_HUMAN

AMDHD2 Antibody (PACO15419)

Description

AMDHD2 Antibody (PACO15419)

Overview

Properties

Product Images

Additional Information

Related Products

	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15419(AMDHD2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: mouse heart tissue, Mouse liver tissue, Primary antibody: PACO15419(AMDHD2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes.
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15419(AMDHD2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).

AMDHD2 Antibody (PACO15419)

Description

AMDHD2 Antibody (PACO15419)

Overview

Properties

Product Images

Additional Information

Related Products

Related Products

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