The AMDHD1 Polyclonal Antibody (PAC039614) is a valuable tool for researchers studying AMDHD1, an enzyme involved in the metabolism of N-acetyl-L-glutamate, a key molecule in the urea cycle. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the AMDHD1 protein, this antibody enables researchers to detect and analyze AMDHD1 expression in various cell types, making it ideal for studies in metabolism, urea cycle disorders, and related conditions.
AMDHD1 plays a crucial role in maintaining nitrogen balance in the body by catalyzing the hydrolysis of N-acetyl-L-glutamate, a process essential for the production of urea. Dysregulation of AMDHD1 activity has been implicated in various metabolic disorders, making it a target of interest in research on conditions such as hyperammonemia and urea cycle disorders. Understanding the function of AMDHD1 is key to developing diagnostic tools and potential treatments for these metabolic conditions.
Antibody Name:
AMDHD1 Antibody (PACO39614)
Antibody SKU:
PACO39614
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Probable imidazolonepropionase protein (1-426AA)
Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1), AMDHD1
UniProt Protein Function:
AMDHD1: Belongs to the HutI family.Protein type: Amino Acid Metabolism - histidine; EC 3.5.2.7; HydrolaseChromosomal Location of Human Ortholog: 12q23.1Cellular Component: cytosolMolecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidesBiological Process: histidine catabolic process
