The Anti-AMD1 Antibody (CAB8537) is a versatile tool for research involving AMD1, an essential enzyme involved in cellular metabolism and proliferation. This polyclonal antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting AMD1 in a variety of samples, particularly in Western blotting applications.AMD1, also known as adenosylmethionine decarboxylase 1, plays a crucial role in polyamine biosynthesis, which is essential for cell growth and survival. Dysregulation of AMD1 has been implicated in various diseases, including cancer and metabolic disorders.
By targeting AMD1, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.With its reliable performance and broad applicability, the Anti-AMD1 Antibody is a valuable tool for studying AMD1 function and its implications in health and disease. Whether investigating cellular pathways, drug development, or biomarker discovery, this antibody offers the precision and reliability needed for cutting-edge research in the fields of biochemistry, cell biology, and pharmacology.
Product Name:
AMD1 Rabbit Polyclonal Antibody
SKU:
CAB8537
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2).
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.
Purification Method:
Affinity purification
Gene ID:
262
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse skeletal muscle, using AMD1 antibody (CAB8537) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
