AMACR Rabbit Polyclonal Antibody (CAB1130)
- SKU:
- CAB1130
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | AMACR Rabbit Polyclonal Antibody |
SKU: | CAB1130 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human AMACR (NP_055139.4). |
Sequence: | MALQ GISV VELS GLAP GPFC AMVL ADFG ARVV RVDR PGSR YDVS RLGR GKRS LVLD LKQP RGAA VLRR LCKR SDVL LEPF RRGV MEKL QLGP EILQ RENP RLIY ARLS GFGQ SGSF CRLA GHDI NYLA LSGV LSKI GR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | RM; RACE; CBAS4; P504S; AMACRD; AMACR |
Positive Sample: | LNCap,Mouse kindey,Mouse liver,Rat kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Peroxisome. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa/43kDa |
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Purification Method: | Affinity purification |
Gene ID: | 23600 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |