The ALS2CR11 Polyclonal Antibody (PAC022143) is a valuable tool for researchers studying ALS2CR11, a protein involved in various cellular processes. This antibody, produced in rabbits, has high specificity for ALS2CR11 in human samples and is suitable for use in Western blot applications. By targeting the ALS2CR11 protein, this antibody allows for the detection and analysis of ALS2CR11 expression in different cell types, making it an essential component for studies in cell biology and molecular biology research.ALS2CR11, a relatively understudied protein, is believed to play a role in cellular function and may be implicated in certain disease processes.
Research into ALS2CR11 could provide valuable insights into its function and potential therapeutic implications in diseases such as neurodegenerative disorders and cancer. By utilizing the ALS2CR11 Polyclonal Antibody, researchers can further explore the role of ALS2CR11 in cellular pathways and disease mechanisms, ultimately advancing our understanding of this protein and its potential applications in biomedical research.
Antibody Name:
ALS2CR11 Antibody (PACO22143)
Antibody SKU:
PACO22143
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human ALS2CR11.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from NIH/3T3 cells, using ALS2CR11 antibody.
Background:
2 isoforms of the human protein are produced by alternative splicing.
Synonyms:
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein;
UniProt Protein Function:
ALS2CR11: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q33.1Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction. [provided by RefSeq, Jun 2016]
