The ALS2CR11 Polyclonal Antibody (PAC015415) is a valuable tool for researchers studying ALS2CR11, a protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to ALS2CR11, the antibody enables accurate detection and analysis of this protein in different cell types, making it ideal for immunology and cancer research studies.
ALS2CR11 is known to play a role in cellular functions related to immune regulation and inflammation. Its involvement in these pathways suggests its potential significance in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying the function of ALS2CR11, researchers may uncover new insights into the mechanisms underlying these diseases, paving the way for potential therapeutic interventions that target ALS2CR11-mediated pathways.
Antibody Name:
ALS2CR11 Antibody (PACO15415)
Antibody SKU:
PACO15415
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human ALS2CR11
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15415(ALS2CR11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene has highly expression in digestive system component and liver, biliary system. It may have four isoforms that produced by alternative splicing. Transcription profiling of human mesenchymal stem cells transformed with lentiviral vectors of TERT, E6, SV40 and RAS.
ALS2CR11: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q33.1Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction. [provided by RefSeq, Jun 2016]
