Alkaline Phosphatase (ALPL) Rabbit Polyclonal Antibody (CAB1080)
- SKU:
- CAB1080
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | Alkaline Phosphatase (ALPL) Rabbit Polyclonal Antibody |
SKU: | CAB1080 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-260 of human Alkaline Phosphatase (ALPL) (NP_000469.3). |
Sequence: | GVKA NEGT VGVS AATE RSRC NTTQ GNEV TSIL RWAK DAGK SVGI VTTT RVNH ATPS AAYA HSAD RDWY SDNE MPPE ALSQ GCKD IAYQ LMHN IRDI DVIM GGGR KYMY PKNK TDVE YESD EKAR GTRL DGLD LVDT WKSF K |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HOPS; HPPA; HPPC; HPPI; HPPO; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP; TNS-ALP; Alkaline Phosphatase (ALPL) |
Positive Sample: | HeLa,Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 57kDa |
Observed MW: | 80kDa |
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
Purification Method: | Affinity purification |
Gene ID: | 249 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |