The ALPK2 Polyclonal Antibody (PAC021888) is a valuable tool for research involving ALPK2, a protein kinase implicated in various cellular processes, including cell proliferation and differentiation. The antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the ALPK2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.
ALPK2, also known as alpha kinase 2, plays a crucial role in regulating cell growth and survival, making it a promising target for investigating diseases such as cancer. Understanding the functions of ALPK2 is essential for unraveling its involvement in cellular processes and identifying potential therapeutic strategies to target ALPK2-mediated pathways. Researchers studying cellular signaling pathways and protein kinases will find the ALPK2 Polyclonal Antibody to be a valuable asset in their experimental work.
Antibody Name:
ALPK2 Antibody (PACO21888)
Antibody SKU:
PACO21888
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ALPK2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Ryazanov A.G., Curr. Biol. 9:R43-R45(1999).
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human heart tissue, using ALPK2 antibody.
Synonyms:
Alpha-protein kinase 2; EC 2.7.11; Heart alpha-protein kinase; ALPK2; HAK
UniProt Protein Function:
AlphaK2: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.Protein type: Kinase, protein; EC 2.7.11.-; Protein kinase, atypical; ATYPICAL group; Alpha familyChromosomal Location of Human Ortholog: 18q21.31Cellular Component: nucleoplasmMolecular Function: ATP binding; protein serine/threonine kinase activityBiological Process: protein amino acid phosphorylation