The ALPK2 Polyclonal Antibody (PACO3401) is a valuable tool for researchers studying the ALPK2 protein, a kinase implicated in various cellular processes such as cell division and DNA damage response. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to ALPK2, this antibody enables the detection and analysis of the protein in different cell types, making it ideal for research in areas such as molecular biology and cancer biology.
ALPK2, also known as Alpha kinase 2, is a key regulator of cell proliferation and survival, making it a potential target for therapeutic interventions in cancer and other diseases involving aberrant cell growth. Its role in DNA damage repair and cell cycle control highlights its importance in maintaining genomic stability and preventing the development of cancerous mutations. By understanding the function of ALPK2, researchers can gain insights into its potential as a therapeutic target for cancer treatment and other related conditions.
Antibody Name:
ALPK2 Antibody
Antibody SKU:
PACO03401
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Alpha-protein Kinase 2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AlphaK2: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.Protein type: Kinase, protein; EC 2.7.11.-; Protein kinase, atypical; ATYPICAL group; Alpha familyChromosomal Location of Human Ortholog: 18q21.31Cellular Component: nucleoplasmMolecular Function: ATP binding; protein serine/threonine kinase activityBiological Process: protein amino acid phosphorylation
