The Alpha Internexin Polyclonal Antibody (CAB3109) is a powerful tool for researchers studying the alpha internexin protein, which plays a key role in neuronal development and maintenance. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including immunohistochemistry and Western blot.Alpha internexin is a cytoskeletal protein expressed in neurons and is essential for maintaining neuronal structure and function. Research has shown that abnormalities in alpha internexin are associated with various neurodegenerative diseases, making it a valuable target for further study in neuroscience and neurology.
By using the Alpha Internexin Polyclonal Antibody (CAB3109), researchers can effectively detect and analyze alpha internexin expression in different cell types and tissues, providing valuable insights into the role of this protein in neuronal health and disease. This antibody is a valuable tool for advancing our understanding of neurodegenerative disorders and developing potential therapies for these conditions.
Product Name:
Alpha Internexin Rabbit Polyclonal Antibody
SKU:
CAB3109
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 13-300 of human Alpha Internexin (Q16352).
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
Purification Method:
Affinity purification
Gene ID:
9118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Alpha Internexin antibody (CAB3109) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.