ACTR1A Rabbit Polyclonal Antibody (CAB6515)
- SKU:
- CAB6515
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ACTR1A Rabbit Polyclonal Antibody |
SKU: | CAB6515 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 187-376 of human ACTR1A (NP_005727.1). |
Sequence: | GRDV SRFL RLYL RKEG YDFH SSSE FEIV KAIK ERAC YLSI NPQK DETL ETEK AQYY LPDG STIE IGPS RFRA PELL FRPD LIGE ESEG IHEV LVFA IQKS DMDL RRTL FSNI VLSG GSTL FKGF GDRL LSEV KKLA PKDV KIRI SAPQ ERLY STWI GGSI LASL DTFK KMWV SKKE YEED GARS IHRK TF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ARP1; Arp1A; CTRN1; ACTR1A |
Positive Sample: | MCF7,Mouse skeletal muscle,Mouse spleen,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Purification Method: | Affinity purification |
Gene ID: | 10121 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |