The Alpha-Beta Synuclein Rabbit Monoclonal Antibody (CAB4899) is a powerful tool for research involving alpha-beta synuclein, a protein associated with neurodegenerative disorders such as Parkinson's disease. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity for detecting alpha-beta synuclein in human samples.Validated for use in Western blot applications, this antibody binds specifically to alpha-beta synuclein, allowing for precise detection and analysis in various cell types. Its reliability and accuracy make it an essential tool for studies in neuroscience and neurodegenerative diseases.Alpha-beta synuclein plays a crucial role in the pathogenesis of Parkinson's disease and other related conditions, making it a valuable target for research aimed at understanding the underlying mechanisms of these disorders.
By studying the activity and expression of alpha-beta synuclein, researchers can gain valuable insights that may lead to the development of novel diagnostic tools and therapeutic interventions for neurodegenerative diseases.Overall, the Alpha-Beta Synuclein Rabbit Monoclonal Antibody (CAB4899) is an indispensable resource for scientists and researchers investigating alpha-beta synuclein and its implications in neurodegenerative disorders. Its high-quality performance and reliability make it a valuable asset in the field of neuroscience research.
Product Name:
alpha + beta Synuclein Rabbit Monoclonal Antibody
SKU:
CAB4899
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human alpha + beta Synuclein (P37840).
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Purification Method:
Affinity purification
Gene ID:
6622/6620
Clone Number:
ARC1181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using alpha + beta Synuclein Rabbit mAb (CAB4899) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
