The Alpha Adducin Polyclonal Antibody (CAB1592) is a valuable tool for researchers studying the alpha adducin protein and its role in cellular function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the alpha adducin protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in cell biology, neuroscience, and cardiovascular research.Alpha adducin is a key regulator of cytoskeletal dynamics and cell signaling pathways, playing a critical role in the maintenance of cell shape and function. Dysregulation of alpha adducin has been implicated in various diseases, including hypertension, kidney disease, and heart failure, making it a promising target for therapeutic interventions.
Understanding the intricate mechanisms by which alpha adducin influences cellular processes is essential for developing novel treatment strategies aimed at addressing these health challenges.Overall, the Alpha Adducin Polyclonal Antibody (CAB1592) provides researchers with a powerful tool to investigate the function and regulation of alpha adducin, shedding light on its impact on cellular physiology and disease pathogenesis. Its high specificity and sensitivity make it a reliable reagent for furthering our understanding of this essential protein in both normal and pathological conditions.
Product Name:
ADD1 Rabbit Polyclonal Antibody
SKU:
CAB1592
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ADD1 (NP_054908.2).
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
Purification Method:
Affinity purification
Gene ID:
118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ADD1 antibody (CAB1592) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
