The Alpha 2 Antiplasmin Polyclonal Antibody (CAB9945) is a vital tool for researchers studying the role of alpha 2 antiplasmin in regulating fibrinolysis, clot formation, and wound healing processes. This high-quality antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting and immunohistochemistry.Alpha 2 antiplasmin is a critical inhibitor of plasmin, the enzyme responsible for breaking down blood clots. Dysregulation of this process can lead to serious health issues, including thrombosis and hemorrhage. By using the Alpha 2 Antiplasmin Polyclonal Antibody, researchers can accurately detect and quantify alpha 2 antiplasmin levels in different biological samples, shedding light on its role in various physiological and pathological conditions.
With its ability to target alpha 2 antiplasmin with high specificity and sensitivity, this antibody is an essential tool for studies in hemostasis, thrombosis, and cardiovascular disease. By understanding the mechanisms of alpha 2 antiplasmin regulation, researchers can uncover new insights into clotting disorders and develop innovative therapeutic strategies to target these conditions effectively.
Product Name:
SERPINF2 Rabbit Polyclonal Antibody
SKU:
CAB9945
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 302-491 of human SERPINF2 (NP_001159392.1).
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5345
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using SERPINF2 Rabbit pAb (CAB9945) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
