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Alpha-1 Antitrypsin (SERPINA1) Monoclonal Antibody (CAB21972)

SKU:
CAB21972
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
€139 - €529
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-1 Antitrypsin (SERPINA1) Monoclonal Antibody
SKU:CAB21972
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-418 of human Alpha-1 Antitrypsin (SERPINA1) (NP_000286.3).
Sequence:EDPQ GDAA QKTD TSHH DQDH PTFN KITP NLAE FAFS LYRQ LAHQ SNST NIFF SPVS IATA FAML SLGT KADT HDEI LEGL NFNL TEIP EAQI HEGF QELL RTLN QPDS QLQL TTGN GLFL SEGL KLVD KFLE DVKK LYHS EAFT VNFG DTEE AKKQ INDY VEKG TQGK IVDL VKEL DRDT VFAL VNYI FFKG KWER PFEV KDTE EEDF HVDQ VTTV KVPM MKRL GMFN IQHC KKLS SWVL LMKY LGNA TAIF FLPD EGKL QHLE NELT HDII TKFL ENED RRSA SLHL PKLS ITGT YDLK SVLG QLGI TKVF SNGA DLSG VTEE APLK LSKA VHKA VLTI DEKG TEAA GAMF LEAI PMSI PPEV KFNK PFVF LMIE QNTK SPLF MGKV VNPT QK
Tested Applications:IF/ICC ELISA
Recommended Dilution:IF/ICC,1:50 - 1:200
Synonyms:PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT; Alpha-1 Antitrypsin (SERPINA1)
Conjugate:Unconjugated
Cellular Localization:Endoplasmic reticulum, Secreted, extracellular matrix, extracellular space.
Calculated MW:47kDa
Observed MW:Refer to figures

The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:5265
Clone Number:ARC54184
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageConfocal imaging of Hep G2 cells using Alpha-1 Antitrypsin (SERPINA1) Rabbit mAb (A21972,at dilution of 1:100) (Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012,dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.

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