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Alpha-1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody (CAB1015)

SKU:
CAB1015
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB1015
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB1015
  • Immunology Antibodies 1 Anti-SERPINA1 Antibody CAB1015
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody
SKU:CAB1015
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 156-255 of human Alpha-1 Antitrypsin (SERPINA1) (NP_000286.3).
Sequence:EDVK KLYH SEAF TVNF GDTE EAKK QIND YVEK GTQG KIVD LVKE LDRD TVFA LVNY IFFK GKWE RPFE VKDT EEED FHVD QVTT VKVP MMKR LGMF NIQH
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT; Alpha-1 Antitrypsin (SERPINA1)
Positive Sample:HepG2,293T,Mouse lung
Conjugate:Unconjugated
Cellular Localization:Endoplasmic reticulum, Secreted, extracellular matrix, extracellular space.
Calculated MW:47kDa
Observed MW:51kDa

The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:5265
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Alpha-1 Antitrypsin (SERPINA1) Rabbit pAb (CAB1015) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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