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Alpha-1 Antichymotrypsin (SERPINA3) Rabbit Monoclonal Antibody (CAB11364)

SKU:
CAB11364
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Immunology
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Alpha-1 Antichymotrypsin (SERPINA3) Rabbit Monoclonal Antibody
SKU:CAB11364
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-423 of human Alpha-1 Antichymotrypsin (SERPINA3) (P01011).
Sequence:MERM LPLL ALGL LAAG FCPA VLCH PNSP LDEE NLTQ ENQD RGTH VDLG LASA NVDF AFSL YKQL VLKA PDKN VIFS PLSI STAL AFLS LGAH NTTL TEIL KGLK FNLT ETSE AEIH QSFQ HLLR TLNQ SSDE LQLS MGNA MFVK EQLS LLDR FTED AKRL YGSE AFAT DFQD SAAA KKLI NDYV KNGT RGKI TDLI KDLD SQTM MVLV NYIF FKAK WEMP FDPQ DTHQ SRFY LSKK KWVM VPMM SLHH LTIP YFRD EELS CTVV ELKY TGNA SALF ILPD QDKM EEVE AMLL PETL KRWR DSLE FREI GELY LPKF SISR DYNL NDIL LQLG IEEA FTSK ADLS GITG ARNL AVSQ VVHK AVLD VFEE GTEA SAAT AVKI TLLS ALVE TRTI VRFN RPFL MIIV PTDT QNIF FMSK VTNP KQA
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:ACT; AACT; GIG24; GIG25; Alpha-1 Antichymotrypsin (SERPINA3)
Positive Sample:Human plasma
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:48kDa
Observed MW:50-70kDa

The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Purification Method:Affinity purification
Gene ID:12
Clone Number:ARC0581
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Alpha-1 Antichymotrypsin (SERPINA3) Rabbit mAb (CAB11364) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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