The Alpha-1-Antichymotrypsin Rabbit Monoclonal Antibody is a valuable tool for researchers studying the alpha-1-antichymotrypsin protein, which is involved in immune regulation and inflammation. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the alpha-1-antichymotrypsin protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.
Alpha-1-antichymotrypsin is a critical component in immune response modulation, and understanding its role is essential for developing therapies for diseases like cancer, autoimmune disorders, and chronic inflammatory conditions. The Alpha-1-Antichymotrypsin Rabbit Monoclonal Antibody aids researchers in furthering their understanding of this protein and its potential as a therapeutic target for various diseases.
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Purification Method:
Affinity purification
Gene ID:
12
Clone Number:
ARC0581
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Alpha-1 Antichymotrypsin (SERPINA3) Rabbit mAb (CAB11364) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
