The ALOX12B Polyclonal Antibody (CAB16210) is a valuable tool for researchers studying the ALOX12B enzyme, which plays a crucial role in the biosynthesis of specialized pro-resolving mediators (SPMs) that regulate inflammation resolution and tissue repair processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.ALOX12B is an essential enzyme involved in the metabolism of arachidonic acid to produce bioactive lipid mediators that play key roles in resolving inflammation and promoting tissue repair.
Dysregulation of ALOX12B has been linked to various inflammatory diseases, making it a potential target for therapeutic interventions. By detecting and analyzing ALOX12B protein expression in different cell types, this antibody can contribute to a better understanding of its function and its implications in inflammatory conditions and related diseases, ultimately aiding in the development of novel treatment strategies.
Product Name:
ALOX12B Rabbit Polyclonal Antibody
SKU:
CAB16210
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALOX12B (NP_001130.1).
This gene encodes an enzyme involved in the conversion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.
Purification Method:
Affinity purification
Gene ID:
242
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat testis, using ALOX12B Rabbit pAb (CAB16210) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
