The ALLC Antibody (PACO07703) is a polyclonal antibody designed for research involving ALLC, a key enzyme involved in DNA demethylation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an ideal tool for studying DNA demethylation processes in various cell types. Validated for use in immunofluorescence and immunohistochemistry applications, the ALLC Antibody binds specifically to the ALLC protein, allowing for detailed analysis and detection in research related to epigenetics and gene expression regulation.ALLC, also known as allantoicase, plays a critical role in the demethylation of DNA, facilitating epigenetic modifications that regulate gene expression and cellular function.
Understanding the functions and regulation of ALLC is essential for advancing research in fields like developmental biology, cancer biology, and neurobiology. The ALLC Antibody provides researchers with a valuable tool to study the role of ALLC in various biological processes and pathological conditions, paving the way for potential therapeutic interventions targeting DNA demethylation mechanisms.
ALLC: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. Belongs to the allantoicase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; Nucleotide Metabolism - purine; EC 3.5.3.4Chromosomal Location of Human Ortholog: 2q35Molecular Function: allantoicase activityBiological Process: allantoin catabolic process
UniProt Protein Details:
NCBI Summary:
Allantoicase (EC 3.5.3.4) participates in the uric acid degradation pathway. Its enzymatic activity, like that of urate oxidase (MIM 191540), was lost during vertebrate evolution.[supplied by OMIM, Nov 2008]
