The ALKBH8 Polyclonal Antibody (CAB7142) is a valuable tool for researchers studying ALKBH8, an enzyme involved in nucleic acid demethylation and RNA modification processes. This antibody, produced in rabbits, has high specificity and sensitivity for detecting ALKBH8 in human samples, making it ideal for use in Western blot applications.ALKBH8, a member of the AlkB family of proteins, plays a crucial role in cellular processes such as DNA repair, RNA metabolism, and gene expression regulation.
Its involvement in nucleic acid demethylation makes it a key player in epigenetic modification pathways and potential target for therapeutic interventions in cancer and other diseases.By using the ALKBH8 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of ALKBH8 in various biological contexts, paving the way for groundbreaking discoveries in the fields of molecular biology, genetics, and cancer research.
Product Name:
ALKBH8 Rabbit Polyclonal Antibody
SKU:
CAB7142
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ALKBH8 (NP_620130.2).
Enables tRNA (uracil) methyltransferase activity; tRNA binding activity; and zinc ion binding activity. Involved in cellular response to DNA damage stimulus; tRNA methylation; and tRNA wobble uridine modification. Located in cytosol and nuclear body. Implicated in autosomal recessive non-syndromic intellectual disability.
Purification Method:
Affinity purification
Gene ID:
91801
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ALKBH8 Rabbit pAb (CAB7142) at 1:14000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
