The ALKBH1 Rabbit Monoclonal Antibody (CAB9221) is a valuable tool for researchers studying ALKBH1, a key enzyme involved in DNA and RNA repair processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting ALKBH1 in human samples and has been validated for use in Western blot applications. By binding specifically to the ALKBH1 protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in molecular biology and cancer research.ALKBH1 is a crucial enzyme involved in repairing alkylated DNA and RNA damage, which is essential for maintaining genomic integrity and preventing mutations that can lead to cancer and other diseases.
Understanding the role of ALKBH1 in DNA and RNA repair mechanisms is vital for identifying potential therapeutic targets for cancer treatment and other genetic disorders. This antibody provides researchers with a reliable means of investigating the function and regulation of ALKBH1 in cellular processes, offering valuable insights into its implications for human health.
Product Name:
ALKBH1 Rabbit Monoclonal Antibody
SKU:
CAB9221
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ALKBH1 (Q13686).
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
Purification Method:
Affinity purification
Gene ID:
8846
Clone Number:
ARC2511
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ALKBH1 antibody (CAB9221) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.