The ALG2 Polyclonal Antibody (CAB15203) is a valuable tool for researchers studying ALG2, a key protein involved in calcium signaling and cellular transport mechanisms. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for detecting ALG2 in human samples, making it ideal for use in Western blot applications.ALG2 is a crucial factor in maintaining proper cellular function, particularly in processes related to protein glycosylation and calcium-induced cell death. By targeting ALG2 with this polyclonal antibody, researchers can gain valuable insights into the mechanisms by which this protein impacts various cellular functions.
This antibody can be utilized in a variety of cell types, offering versatility and reliability for studies in cell biology and related fields.Overall, the ALG2 Polyclonal Antibody (CAB15203) provides a powerful tool for investigating the roles of ALG2 in cellular physiology and pathology, offering new opportunities for understanding and potentially targeting this protein in research related to diseases such as cancer and neurodegenerative disorders.
Product Name:
ALG2 Rabbit Polyclonal Antibody
SKU:
CAB15203
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 197-416 of human ALG2 (NP_149078.1).
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
85365
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using ALG2 antibody (CAB15203) at dilution of 1:100. Blue: DAPI for nuclear staining.