Anti-ALG12 Antibody (PACO15385)

Antibody Name:	ALG12 Antibody (PACO15385)
Antibody SKU:	PACO15385
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Fusion protein of human ALG12

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15385(ALG12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using PACO15385(ALG12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).

Background:

This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.

Synonyms:

ALG12, alpha-1,6-mannosyltransferase

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:	This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008]
UniProt Code:	Q9BV10
NCBI GenInfo Identifier:	13129114
NCBI Gene ID:	79087
NCBI Accession:	NP_077010
UniProt Secondary Accession:	Q9BV10
UniProt Related Accession:	Q9BV10
Molecular Weight:	53kDa
NCBI Full Name:	dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
NCBI Synonym Full Names:	ALG12 alpha-1,6-mannosyltransferase
NCBI Official Symbol:	ALG12
NCBI Official Synonym Symbols:	CDG1G; ECM39; hALG12; PP14673
NCBI Protein Information:	dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
UniProt Protein Name:	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
UniProt Synonym Protein Names:	Asparagine-linked glycosylation protein 12 homolog; hALG12; Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; Mannosyltransferase ALG12 homolog; Membrane protein SB87
Protein Family:
UniProt Gene Name:	ALG12
UniProt Entry Name:	ALG12_HUMAN

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)