The ALDH6A1 Polyclonal Antibody (CAB3309) is a crucial tool for researchers studying ALDH6A1, a key enzyme involved in the metabolism of amino acids and the detoxification of aldehydes. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By binding to the ALDH6A1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential resource for studies in biochemistry and toxicology.ALDH6A1 plays a vital role in the breakdown of amino acids for energy production and maintenance of cellular health. Dysregulation of this enzyme has been implicated in various diseases, including metabolic disorders and neurodegenerative conditions.
By investigating the function of ALDH6A1, researchers can gain valuable insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets for intervention.The ALDH6A1 Polyclonal Antibody is a valuable tool for studying the role of ALDH6A1 in cellular metabolism and disease pathology. Its specificity and reliability make it an indispensable asset for scientists conducting research in fields such as biochemistry, pharmacology, and neuroscience. Explore the functions of ALDH6A1 with confidence using this high-quality antibody as a key component of your experimental toolbox.
Product Name:
ALDH6A1 Rabbit Polyclonal Antibody
SKU:
CAB3309
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human ALDH6A1 (NP_005580.1).
This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ALDH6A1 antibody (CAB3309) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
