The ALDH3A2 Polyclonal Antibody (CAB16267) is a powerful tool for research involving ALDH3A2, an important enzyme involved in the detoxification of aldehydes. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding specifically to the ALDH3A2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in biochemistry and toxicology.ALDH3A2, also known as aldehyde dehydrogenase 3 family member A2, plays a crucial role in protecting cells from the harmful effects of aldehydes by converting them into non-toxic molecules.
Dysregulation of ALDH3A2 has been implicated in a variety of diseases, including cancer and oxidative stress-related disorders. Understanding the function of ALDH3A2 is essential for developing targeted therapies aimed at mitigating the effects of aldehyde-induced damage in these pathological conditions.Overall, the ALDH3A2 Polyclonal Antibody (CAB16267) offers researchers a reliable tool for investigating the role of ALDH3A2 in cellular detoxification processes, providing valuable insights into potential therapeutic strategies for aldehyde-related diseases.
Product Name:
ALDH3A2 Rabbit Polyclonal Antibody
SKU:
CAB16267
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-320 of human ALDH3A2 (NP_001026976.1).
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
224
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ALDH3A2 Rabbit pAb (CAB16267) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
