ALDH3A1 Rabbit Polyclonal Antibody (CAB5502)
- SKU:
- CAB5502
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ALDH3A1 Rabbit Polyclonal Antibody |
SKU: | CAB5502 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ALDH3A1 (NP_001128640.1). |
Sequence: | MSKI SEAV KRAR AAFS SGRT RPLQ FRIQ QLEA LQRL IQEQ EQEL VGAL AADL HKNE WNAY YEEV VYVL EEIE YMIQ KLPE WAAD EPVE KTPQ TQQD ELYI HSEP LGVV LVIG TWNY PFNL TIQP MVGA IAAG NSVV LKPS ELSE NMAS LLAT IIPQ YLDK DLYP VING GVPE TTEL LKER FDHI LYTG STGV GKII MTAA AKHL TPVT LELG GKSP CYVD KNCD LDVA CRRI AWGK FMNS GQTC VAPD YILC DPSI QNQI VEKL KKSL KEFY GEDA KKSR DYGR IISA RHFQ RVMG LIEG |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | ALDH3; ALDHIII; ALDH3A1 |
Positive Sample: | A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 50kDa |
Observed MW: | 55kDa |
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 218 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |