ALDH1L1 Rabbit Polyclonal Antibody (CAB7067)
- SKU:
- CAB7067
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ALDH1L1 Rabbit Polyclonal Antibody |
SKU: | CAB7067 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2). |
Sequence: | MKIA VIGQ SLFG QEVY CHLR KEGH EVVG VFTV PDKD GKAD PLGL EAEK DGVP VFKY SRWR AKGQ ALPD VVAK YQAL GAEL NVLP FCSQ FIPM EIIS APRH GSII YHPS LLPR HRGA SAIN WTLI HGDK KGGF SIFW ADDG LDTG DLLL QKEC EVLP DDTV STLY NRFL FPEG IKGM VQAV RLIA EGKA PRLP QPEE GATY EGIQ KKET AKIN WDQP AEAI HNWI RGND KVPG AWTE ACEQ KLTF FNST LN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FDH; FTHFD; 10-fTHF; 10-FTHFDH; ALDH1L1 |
Positive Sample: | MCF7,Mouse brain,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 99kDa |
Observed MW: | 120kDa |
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10840 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |