The ALDH1B1 Polyclonal Antibody (CAB15025) is specifically designed for research involving ALDH1B1, an enzyme from the aldehyde dehydrogenase family that plays a crucial role in the detoxification of aldehydes generated by alcohol metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blotting.ALDH1B1 is known for its involvement in the metabolism of acetaldehyde, a toxic byproduct of alcohol consumption. Its expression in certain tissues has been linked to increased resistance to the harmful effects of alcohol, making it an interesting target for studies related to alcohol metabolism and its associated diseases such as alcoholism and liver damage.
This antibody binds specifically to the ALDH1B1 protein, allowing for its detection and analysis in various cell types and tissues. Its utility in research on alcohol metabolism, liver function, and related diseases makes it a valuable tool for scientists seeking to understand the mechanisms underlying these conditions and develop potential therapeutic interventions.
Product Name:
ALDH1B1 Rabbit Polyclonal Antibody
SKU:
CAB15025
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3).
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.
Purification Method:
Affinity purification
Gene ID:
219
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using ALDH1B1 antibody (CAB15025) at dilution of 1:100. Blue: DAPI for nuclear staining.
